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Noboru Hioka Selected Research

1-phenyl-3,3-dimethyltriazene (PDT)

4/2022Elucidation the binding interaction of hypericin-loaded P84 copolymeric micelles by using 1D and 2D NMR techniques.
9/2021Hypericin-P123-photodynamic therapy in an ex vivo model as an alternative treatment approach for onychomycosis caused by Fusarium spp.
8/2020Selective photodynamic effects on cervical cancer cells provided by P123 Pluronic®-based nanoparticles modulating hypericin delivery.
1/2020Photodamage on Staphylococcus aureus by natural extract from Tetragonia tetragonoides (Pall.) Kuntze: Clean method of extraction, characterization and photophysical studies.
1/2020Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery.
1/2018Biomedical Platform Development of a Chlorophyll-Based Extract for Topic Photodynamic Therapy: Mechanical and Spectroscopic Properties.
5/2017Response surface method optimization of a novel Hypericin formulation in P123 micelles for colorectal cancer and antimicrobial photodynamic therapy.
1/2015Topical and Intradermal Efficacy of Photodynamic Therapy with Methylene Blue and Light-Emitting Diode in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis.
6/2012Antibacterial photodynamic therapy for dental caries: evaluation of the photosensitizers used and light source properties.
8/2011Photodynamic therapy for American cutaneous leishmaniasis: the efficacy of methylene blue in hamsters experimentally infected with Leishmania (Leishmania) amazonensis.

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Noboru Hioka Research Topics

Disease

14Neoplasms (Cancer)
04/2022 - 01/2016
3Phototoxic Dermatitis (Phototoxicity)
01/2020 - 02/2017
3Cutaneous Leishmaniasis
04/2019 - 08/2011
2Melanoma (Melanoma, Malignant)
12/2022 - 05/2020
2Infections
01/2021 - 01/2020
2Necrosis
08/2020 - 01/2020
2Leishmaniasis
04/2019 - 01/2018
2Dental Caries (Decay, Dental)
09/2016 - 06/2012
1Onychomycosis (Tinea Unguium)
09/2021
1Mycoses (Diseases, Fungus)
09/2021
1Uterine Cervical Neoplasms (Cancer of the Cervix)
08/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Breast Neoplasms (Breast Cancer)
01/2020
1Neglected Diseases
04/2019
1Photosensitivity Disorders (Photodermatitis)
01/2019
1Colonic Diseases
05/2017
1Colorectal Neoplasms (Colorectal Cancer)
05/2017
1Surgical Wound Infection
05/2017
1Carcinoma (Carcinomatosis)
05/2017
1Lung Neoplasms (Lung Cancer)
09/2016
1Inflammation (Inflammations)
01/2015
1Wounds and Injuries (Trauma)
08/2011

Drug/Important Bio-Agent (IBA)

101-phenyl-3,3-dimethyltriazene (PDT)IBA
04/2022 - 08/2011
7MicellesIBA
12/2022 - 01/2016
6hypericinIBA
12/2022 - 05/2017
6Photosensitizing Agents (Photosensitizers)IBA
01/2021 - 06/2012
4UCON 50-HB-5100 (F127)IBA
11/2019 - 01/2016
3Liposomes (Liposome)IBA
11/2020 - 11/2019
3Poloxamer (Poloxamer 407)IBA
01/2020 - 09/2016
2Reactive Oxygen Species (Oxygen Radicals)IBA
09/2021 - 01/2020
2Oxygen (Dioxygen)IBA
01/2020 - 09/2016
2Biotin (Vitamin H)FDA Link
11/2019 - 09/2016
2pluronic block copolymer P123IBA
05/2017 - 02/2017
2Verteporfin (Visudyne)FDA Link
02/2017 - 01/2016
2Methylene Blue (Methylthioninium Chloride)FDA Link
01/2015 - 08/2011
1Folic Acid (Vitamin M)FDA LinkGeneric
12/2022
1SpermineIBA
12/2022
1Aluminum ChlorideIBA
01/2021
1phthalocyanineIBA
01/2021
1PolymersIBA
11/2020
1LipidsIBA
11/2020
1AnnexinsIBA
01/2020
1Propidium (Propidium Iodide)IBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2020
1Trypan BlueFDA Link
01/2020
1AvidinIBA
11/2019
1biotin receptorIBA
11/2019
1EstersIBA
03/2019
1Rose BengalIBA
01/2019
16- astatomethyl- 19- norcholest- 5(10)- en- 3- olIBA
09/2016
1NiclosamideFDA Link
09/2016
1Cisplatin (Platino)FDA LinkGeneric
09/2016
1HalogensIBA
09/2016
1Singlet OxygenIBA
09/2016
1Erythrosine (Erythrosin)IBA
09/2016
1Sorafenib (BAY 43-9006)FDA Link
01/2016
1CollagenIBA
01/2015

Therapy/Procedure

13Photochemotherapy (Photodynamic Therapy)
12/2022 - 08/2011
6Therapeutics
09/2021 - 08/2011
3Precision Medicine
11/2020 - 02/2017
2Drug Therapy (Chemotherapy)
04/2019 - 09/2016